Reporter gene system for use in cell-based assessment of inhibitors of the hepatitis c virus protease
CA 2328494 A1 · Owner: Jackson, Roberta Lynn · Inventors: Potts, Karen Elizabeth; Patick, Amy Karen; Jackson, Roberta Lynn
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A cell-based assay system in which the detection of the reporter gene activity, or secreted alkaline phosphatase (SEAP) is dependent upon the , protease activity of the Hepatitis C virus NS3 gene product. This system can be used to assess the activity of candidate protease inhibitors in a mammalian cell-based assay system. The assay system is simpler than previously described assays due to the use of SEAP which allows the reporter gene activity to be quantified by measuring the amount of secreted gene product in the cell media by monitoring the conversion of luminescent or colorimetric alkaline phosphatase substrate.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 2, 1999. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended August 2, 2019.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 2, 2021.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.