Methods and compositions for the selective expansion of gamma/delta t-cells
CA 2323080 A1 · Owner: Emory University · Inventors: Negrin, Robert; Lopez, Richard; Waller, Edmund K.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides a method of increasing the percentage of gamma/delta T-cells in a population of hematolymphoid cells and which gamma/delta T-cells can survive for a prolonged period comprising: a) , contacting a population of hematolymphoid cells with interleukin 12 and a ligand of CD2 which induces responsiveness to interleukin 12; and b) contacting the cells of step (a) with an antibody to CD3 and interleukin-2. The present invention also provides a method of treating cancer treating an , infection, promoting wound healing and enhancing bone marrow engraftment in a subject comprising administering to the subject an effective amount of the cells of this invention.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 12, 1999. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 12, 2019.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 12, 2021.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.