Methods to provoke anti-cancer immune responses

Abstract From the Canadian patent

The present invention provides methods for inducing an antigen-specific immune response. In one aspect, an effective amount of an antigenic peptide binding protein (APBP) and a cytotoxic agent are administered to the subject. In another aspect, an effective amount of a first polynucleotide encoding an antigenic peptide binding protein and a second polynucleotide encoding a cytotoxic agent are administered to the subject. In another aspect the , methods described herein also include administering an effective amount of an antigen presenting cell (APC) recruitment factor a cytokine or a co-, stimulatory molecule. In yet another embodiment the cytotoxic agent and the , antigen presenting …