Gene therapy of tumors using non-viral delivery system
CA 2321972 A1 · Owner: Perez-Soler, Roman · Inventors: Zou, Yiyu; Perez-Soler, Roman
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides a pharmaceutical composition comprising: (a) cationic lipids, wherein said lipids are a liposomal mixture of a diacyl-ethylphosphocholine and 1,2-diacyl-sn-glycero-3-phosphoethanolamine; and (b) a plasmid cDNA sequence encoding a protein having tumor suppressor or proapoptotic activity. This composition has a high gene transfection efficiency at non-toxic doses and is designed to transfect human bronchial premalignant lesions and early endobronchial malignancies. Also provided is a method of treating a cancerous or pre-cancerous condition of the respiratory tract in an individual in need of such treatment, comprising the step of administering to said …
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 6, 1999. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended January 6, 2019.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 6, 2021.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.