Methods for identifying polycationic, peptide-like compounds with antibacterial activity
CA 2321931 A1 · Owner: Cajal, Yolanda · Inventors: Cajal, Yolanda; Van Dyk, Tina K.; Jain, Mahendra Kumar
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A method is provided for identifying polycationic peptide-like compounds , characterized by antibacterial activity against gram negative bacteria. The method takes advantage of the induction of hyperosomotic stress without leakage of cytoplasmic content. The method involves determining whether the compound has the ability to produce phospholipid exchange betwen the lipid bilayers in conjunction with the induction of the osmotic stress response in the target cell. Determining the induction of the osmotic stress response is effected using a bioluminescent detector organism having a osmY-LUX gene fusion.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 5, 1999. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 5, 2019.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 5, 2021.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.