Cytotoxic alkaloid derivatives including asmarine a and b isolated from a sponge
CA 2316308 A1 · Owner: Instituto Biomar S.A. · Inventors: Kashman, Yoel; Yosief, Tesfamariam; Rudi, Amira
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Asmarine A and B, novel cytotoxic diterpene-alkaloids have been isolated from , the sponge Raspailia sp. The structure of these compounds have been established on the basis of NMR data and confirmed by X-ray analysis. Also claimed are compounds (I) or (II), wherein R1 represents hydrogen or lower alkyl or lower alkanoyl; R2 represents hydrogen or lower alkyl; R3 is either an alkyl or a cycloalkyl group containing one or more isopreneunits or a , monoterpene or a sesquiterpene or a sesquiterpene or a diterpene group; R4 or R5 represent hydrogen or lower alkyl; R6 represents lower alkyl; X represents F or Cl or Br or (I).
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 23, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 23, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 23, 2020.
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.