Nucleic acid ligand diagnostic biochip

Abstract From the Canadian patent

A nucleic acid ligand "biochip" is disclosed consisting of a solid support to , which one or more specific nucleic acid ligands is attached in a spatially defined manner. Each nucleic acid ligand binds specifically and avidly to a particular target molecule contained within a test mixture such as a bodily , fluid. The target molecules include but are not limited to, proteins , (cellular viral, bacterial, etc.) hormones, sugars metabolic byproducts, cofactor, and intermediates drugs, and toxins. Contacting the test mixture with the biochip leads to the binding of a target molecule to its cognate nucleic acid ligand. Binding of target to the nucleic acid ligand results in a detectable …