Method and cells to screen combinatorial libraries
CA 2310381 A1 · Owner: Von Gabain, Alexander · Inventors: Hirsh, Aaron; Von Gabain, Alexander
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
This invention is a method for identifying and isolating at least one of the following: a polypeptide of interest and/or a gene thereof; a target compound and/or a gene thereof, wherein the polypeptide of interest or the target , compound, or both are unknown. The method is based on the steps of: (1) displaying a library of a polypeptide of interest on the surface of a population of prokaryotic or eukaryotic cells; (2) exposing the population to a target compound; and (3) exposing the population to a selection agent. Interaction among the three components "imprints" the polypeptide: that is the interaction selects for those cells in which the polypeptide interacts with the target …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 7, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 7, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 7, 2020.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.