Blocking cell-division as a therapeutic treatment of pathogenic bacteria
CA 2308260 A1 · Owner: Dillon, Jo-Anne R. · Inventors: Szeto, Jason; Dillon, Jo-Anne R.; Ramirez-Arcos, Sandra
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Min proteins are involved in cell division site selection in bacteria. Using Neisseria, gonorrhoeae as a model to study the role of Min proteins a min cluster , containing, homologues of minC minD and minE was identified. N. gonorrhoeae (Ng) CH811 minC and minD insertional mutants exhibited aberrant division patterns in , some, cases producing burst cells indicating that cell division site selection was disrupted. These mutants also presented delayed growth and altered viability. When gonococcal min genes were expressed individually as a cluster, or as fusions , to, green fluorescent protein (GFP) in E. coli PB103 minicells and/or filaments , were, produced indicating that these min genes …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 26, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 26, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 26, 2022.
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.