Dopamine transporter imaging ligand
CA 2305754 A1 · Owner: Research Triangle Institute · Inventors: Abraham, Philip; Kuhar, Michael J.; Boja, John W.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The 3.alpha. isomer of RTI-55, RTI-352 is an effective in vivo binding ligand that reflects greater selectivity for the dopamine transporter than is observed with RTI-55. In addition, there is also a more rapid achievement of apparent equilibrium in the striatal-to-cerebellar ratio (compared to RTI-55) as the ratio peaks at about 30 min and is maintained for about 20 min thereafter. Such apparent equilibrium is useful in developing an approach to measuring the number of dopamine transporters present in tissues. Moreover these results indicate that the utilization of 3.alpha. isomers of a variety of 3.beta. (substituted phenyl) tropanes will result in greater selectivity for dopamine …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed October 7, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended October 7, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 7, 2020.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.