Expression of endogenous genes by non-homologous recombination of a vector construct with cellular dna
CA 2304642 C · Owner: Harrington, John J. · Inventors: Harrington, John J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates generally to activating gene expression or causing over-expression of a gene by recombination methods in situ. The invention also relates generally to methods for expressing an endogenous gene in a cell at levels higher than those normally found in the cell. In one embodiment of the invention, expression of an endogenous gene is activated or increased following integration into the cell by non-homologous or , illegitimate recombination of a regulatory sequence that activates expression of the gene. In another embodiment, the expression of the endogenous gene may be further increased by co-integration of one or more amplifiable markers and , selecting for …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 25, 1998 and granted November 18, 2014. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended September 25, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 25, 2020.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.