Sag: sensitive to apoptosis gene
CA 2303483 A1 · Owner: Sun, Yi · Inventors: Sun, Yi
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides novel genes and polypeptides derived therefrom encoding a redox-sensitive protein that promotes cell growth protects cells , from apoptosis, scavenges oxygen radicals and can be used for the reversion of a tumor phenotype. In an attempt to identify gene(s) responsible for 1,10phenanthroline (OP)-induced apoptosis in tumor cells we have used the differential display technique and cloned an OP-inducible gene SAG (Sensitive , to Apoptosis Gene). SAG encodes a novel redox-sensitive, heme-binding protein with a zinc RING finger domain. The SAG protein consists of 113 amino acids with a calculated molecular weight of 12.7 kDa. Antisense SAG transfection …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 15, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 15, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 15, 2020.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.