Method for crystallizing maleic acid salt of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanyl-l-proline
CA 2302832 A1 · Owner: Fuse, Yoshihide · Inventors: Fuse, Yoshihide; Kinoshita, Koichi; Ueda, Yasuyoshi
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A method for crystallizing the maleic acid salt of N-(1(S)-ethoxycarbonyl-3phenylpropyl)-L-alanyl-L-proline (Enalapril) from an aqueous liquid with ease in good yield, which comprises mixing an aqueous liquid containing N-(1(S)ethoxycarbonyl-3-phenylpropyl)-L-alanyl-L-proline maleic acid and a base and , having a pH of 4 or more with an acid in an amount of the acid sufficient to convert the base to a neutral salt, to thereby crystallize N-(1(S)ethoxycarbonyl-3-phenylpropyl)-L-alanyl-L-proline in the form of a maleic acid salt.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 19, 1999. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended July 19, 2019.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 19, 2021.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.