Sr-bi antagonists and use thereof as contraceptives and in the treatment of steroidal overproduction
CA 2302403 A1 · Owner: Krieger, Monty · Inventors: Krieger, Monty
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
SR-BI is present on the membranes of hepatocytes and steroidogenic tissues including the adrenal gland, testes, and ovaries where it mediates the uptake , and transport of cholesteryl ester from high density lipoproteins. It has been demonstrated that transgenic animals which do not produce SR-BI are perfectly healthy, with the exception that the females are infertile. This provides evidence that inhibition of uptake, binding or transport of cholesteryl ester to SR-BI can be used to inhibit pregnancy. The same pathway can also be used to decrease production of steroids, and therefore be used as a therapy for disorders involving steroidal overproduction.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 4, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended September 4, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 4, 2020.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.