Methods for the high-resolution identification of solvent-accessible amide hydrogens in polypeptides
CA 2300100 A1 · Owner: Woods, Virgil L. Jr. · Inventors: Woods, Virgil L. Jr.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides methods whereby the positions of peptide amide groups that are labeled with a heavy hydrogen in a polypeptide or protein can be localized at high resolution. The methods are useful for determining which peptide amide groups in a polypeptide or protein are accessible to solvent mapping the binding site and/or binding surface of a binding protein and/or , studying allosteric or other conformational changes in a polypeptide or protein which alter the rates at which certain peptide amide hydrogens exchange with solvent.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 18, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended August 18, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 18, 2020.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.