Method for producing cyclic .alpha.-amino acids free from enantiomers or their n-protected derivatives by means of a d-specific aminoacylase

Abstract From the Canadian patent

The invention relates to new microorganisms capable of utilising a N-protected cyclic amino acid derivative, selected from the compounds of the general formula (I), in the form of the racemate or one of its optical isomers where , A together with -N- and -CH is a possibly substituted 4- 5-, 6-, or 7-, membered heterocyclic ring and R1 is a possibly substituted alkyl alkoxy, aryl or aryloxy, and/or are capable of hydrolizing a N-protected cyclic amino acid derivative, selected from among the compounds of the general formula (I) as well as to enzyme extracts thereof. The invention also relates to a new method for producing N-protected cyclic L-amino acid derivatives and cyclic Damino …