Methods of unfolding proteins using metal complexes
CA 2297362 A1 · Owner: Dori, Zvi · Inventors: Blum, Ofer; Dori, Zvi; Gray, Harry B.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to methods of unfolding proteins using metal complexes particularly cobalt-containing Schiff's base compounds. The proteins can be viral proteins or myoglobin, and the unfolding can be irreversible under physiological conditions. The unfolded proteins exhibit UV/vis absorption spectral changes (see the figure) and a 5 % or greater change in at least one minima or maxima of the circular dichroism spectra of the proteins.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 16, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended July 16, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 16, 2020.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.