Utilization of wolinella succinogenes asparaginase to treat diseases associated with asparagine dependence
CA 2295980 A1 · Owner: Durden, Donald L. · Inventors: Durden, Donald L.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Described herein are methods for producing recombinant forms of asparaginase derived from Wolinella succinogenes. In addition methods for covalent , modification of proteins including asparaginases, by acylation are also provided. Certain embodiments provide for epitopic-labeling of the amino terminus of W. succinogenes asparaginase. Additional embodiments concern methods for the therapeutic utilization of the native homotetrameric form of , W. succinogenes asparaginase as well as the use of epitopically-labeled or non-epitopically-labeled recombinant W. succinogenes asparaginase (or a covalently modified analog thereof) in the therapeutic treatment of malignant and non-malignant …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 9, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended June 9, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 9, 2020.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.