Reagents and methods useful for detecting diseases of the lung

Abstract From the Canadian patent

A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as LS170 and transcribed from lung tissue is , described. These sequences are useful for the detecting diagnosing, staging, monitoring, prognosticating in vivo imaging, preventing or treating or , determining the predisposition of an individual to diseases and conditions of the lung, such as lung cancer. Also provided are antibodies which specifically bind to a LS170-encoded polypeptide or protein and agonists or inhibitors , which prevent action of tissue-specific LS170 polypeptides which molecules , are useful for the therapeutic treatment of lung diseases tumors, or , metastases.