Zinc finger protein derivatives and methods therefor
CA 2291861 C · Owner: Barbas, Carlos F. Iii · Inventors: Gottesfeld, Joel M.; Barbas, Carlos F. Iii; Wright, Peter E.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Zinc finger proteins of the Cys2His2 type represent a class of malleable DNA binding proteins which may be selected to bind diverse sequences. Typically zinc finger proteins containing three zinc finger domains like the murine , transcription factor Zif268 and the human transcription factort Sp1 bind nine , contiguous base pairs (bp). To create a class of proteins which would be generally applicable to target unique sites within complex genomes the , present invention provides a polypeptide linker that fuses two three-finger proteins. Two six-fingered proteins were created and demonstrated to bind 18 contiguous bp of DNA in a sequence specific fashion. Expression of these proteins as …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 27, 1998 and granted August 27, 2013. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended May 27, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 27, 2020.
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.