Calibration of fluorescence resonance energy transfer in microscopy
CA 2291730 A1 · Owner: Dilworth, Michael R. · Inventors: Coleman, William J.; Youvan, Douglas C.; Silva, Christopher M.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Imaging hardware, software, calibrants and methods are provided to visualize and quantitate the amount of Fluorescence Resonance Energy Transfer (FRET) occurring between donor and acceptor molecules in epifluorescence microscopy (1). The MicroFRET system compensates for overlap among donor acceptor and , FRET spectra using well characterized fluorescent beads as standards in conjunction with radiometrically calibrated image processing techniques. The MicroFRET system also provides precisely machined epifluorescence cubes (4) to maintain proper image registration as the sample is illuminated (3) at the donor and acceptor excitation wavelengths. Algorithms are described that …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 5, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended June 5, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 5, 2020.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.