Ricin-like toxin variants for treatment of cancer, viral or parasitic infections
CA 2288943 C · Owner: Twinstrand Holdings Inc. · Inventors: Borgford, Thor
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides a protein having an A chain of a ricin-like toxin, a B chain of a ricin-like toxin and a heterologous linker amino acid sequence, linking the A and B chains. The linker sequence contains a cleavage recognition site for a disease specific protease such as a cancer fungal, viral or parasitic protease. The invention also relates to a nucleic acid molecule encoding the protein and to expression vectors incorporating the nucleic acid molecule. Also provided is a method of inhibiting or destroying mammalian cancer cells, cells infected with a virus a fungus, or parasite, or , parasites utilizing the nucleic acid molecules and proteins of the invention and …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 30, 1998 and granted February 1, 2011. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended April 30, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 30, 2020.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.