Benzoyl amino acid derivatives useful as inhibitors of protein isoprenyl tranferases
CA 2288330 C · Owner: Augeri, David J. · Inventors: Liu, Gang; Tasker, Andrew S.; Sullivan, Gerard M.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Compounds having formula (I) or a pharmaceutically acceptable salt thereof wherein R1 is (a) hydrogen, (b) lower alkyl (c) alkenyl, (d) alkoxy, (e) , thioalkoxy (f) halo, (g) haloalkyl, (h) aryl -L2and (i) heterocyclic -L2-; , R2 is selected from (a) formula (1) (b) -C(O)NH-CH(R14)-C(O)OR15, (c) formula (2), (d) -C(O)NH-CH(R14)-C(O)NHSO2R16, (e) -C(O)NH-CH(R14)-tetrazolyl (f) -, C(O)NH-heterocyclic, and (g) -C(O)NH-CH(R14)-C(O)NR17R18; R3 is substituted or unsubstituted heterocyclic or aryl, substituted or unsubstituted cycloalkyl or cycloalkenyl, formula (3), and -P(W)RR3RR3'; R4 is hydrogen lower alkyl, haloalkyl, halogen, aryl, arylalkyl heterocyclic, or (heterocyclic)alkyl; L1 is …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 7, 1998 and granted February 11, 2014. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended May 7, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 7, 2020.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
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