Direct expression of peptides into culture media
CA 2285658 C · Owner: Ray, Martha V. L. · Inventors: Ray, Martha V. L.; Consalvo, Angelo P.; Meenan, Christopher P.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Expression systems are disclosed for the direct expression of peptide products into the culture media where genetically engineered host cells are grown. High yield was achieved with novel vectors a special , selection of hosts, and/or fermentation processes which include careful control of cell growth rate and use of an inducer during , growth phase. Special vectors are provided which include control regions having multiple promoters linked operably with coding regions encoding a signal peptide upstream from a coding region encoding the peptide of interest. Multiple transcription cassettes are also used to increase yield. The production of amidated peptides using the expression …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 15, 1998 and granted October 4, 2011. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended April 15, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 15, 2020.
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Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.