Method for determining cytokine receptor activation by the use of an antibody
CA 2285036 A1 · Owner: Mellado Garcia, Jose Mario · Inventors: Rodriguez Frade, Jose Miguel; Kremer Baron, Leonor; Mellado Garcia, Jose Mario
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to a method for determinating cytokine receptor especially growth hormone receptor (GHR) activation, by the use of an , antibody capable of discrimating between an activated and an inactive cytokine receptor conformation, especially GHR or growth hormone binding protein (GHBP) conformation, the method comprising: contacting the antibody and the cytokine receptor to form a complex, contacting a candidate ligand to the complex measuring the antibody binding to inactive cytokine receptor and thereby discriminating between an activated and an inactive conformation. It also relates to a method for screening for functionally cytokine agonists and antagonists, …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 19, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 19, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 19, 2020.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.