Aqueous immunologic adjuvant compositions of monophosphoryl lipid a
CA 2284586 C · Owner: Corixa Corporation · Inventors: Crane, R. Thomas
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
An aqueous adjuvant composition comprising an attenuated lipid A derivative and a surfactant or surfactants enhances the immunological response in a warm blooded animal to a protein antigen. Attenuated lipid A derivatives useful according to the subject invention include monophosphoryl lipid A and 3-O-deacylated monophosphoryl lipid A. A surfactant or mixtures of surfactants are dissolved in a solvant. 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine is a preferred surfactant. The dissolved surfactant is added to an attenuated lipid A derivative to obtain a mixture. The molar ratio of attenuated lipid A derivative to surfactant in the mixture is about 4:1. The solvent is evaporated and …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
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- Filed April 1, 1998 and granted February 8, 2011. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended April 1, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 1, 2020.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.