Shuffling of heterologous dna sequences
CA 2284097 A1 · Owner: Novo Nordisk A/S · Inventors: Kretzschmar, Titus; Borchert, Torben Vedel; Cherry, Joel R.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to a new method of shuffling especially heterologous polynucleotide sequences, screening and/or selection of new recombinant proteins resulting therefrom having a desired biological activity and especially to production and identification of novel proteases exhibiting desired properties. The method comprises the following steps; i) identification of at least one conserved region between the heterologous sequences of interest; ii) generating fragments of each of the heterologous sequences of interest, wherein said fragments comprise the conserved region(s), in a preferred embodiment due to the use of parts of the regions(s) as primers; and iii) …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 18, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 18, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 18, 2020.
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Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.