Anti-mitotic agents which inhibit tubulin polymerization
CA 2283471 A1 · Owner: Pinney, Kevin G. · Inventors: Shirali, Anupama; Mocharla, Vani P.; Pettit, George R.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Methoxy and ethoxy substituted 3-aroyl-2-arylbenzobthiophenes and benzobthiophene analogues are described for use in inhibiting tubulin polymerization. The compounds' use for treating tumor cells is also described. Additional aspects described here are certain diaryl ether benzobthiophene derivatives. Also described are particular analogs derived from dihydronaphthalene which have proven particularly effective. Certain new benzofuran analogs are described, as well as certain sulfur oxide benzobthiophene analogs. Important compounds described herein include the first nitrogen-containing derivatives of combretastatin. These include nitro amino and azide combretastatin derivatives.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 6, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 6, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 6, 2020.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.