Lipase catalyzed dynamic resolution of isoxazoline thioesters to isoxazoline carboxylic acids
CA 2283234 A1 · Owner: Dupont Pharmaceuticals Company · Inventors: Zhang, Lin-Hua; Pesti, Jaan A.; Anzalone, Luigi
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates generally to a novel lipase catalyzed transesterification for preparation of substituted isoxazolin-5-yl acetic acid in high optical purity from a stereoisomeric mixture of an esterified substituted isoxazolin-5-yl acetate. The products are useful in the synthesis of compounds for pharmaceuticals, especially the treatment of thrombolytic disorders, and agricultural products.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 26, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 26, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 26, 2020.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.