Methods and compositions for modulating responsiveness to corticosteroids
CA 2282845 A1 · Owner: Tracey, Daniel E. · Inventors: Tracey, Daniel E.; Carter, Adam; Ghayur, Tariq
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Method for modulating responsiveness to corticosteroids in a subjet are provided. In the method of the invention an agent which antagonizes a target , that regulates production of IFN-.gamma. in the subject is administered to the subject in combination with a corticosteroid such that responsiveness of the subject to the corticosteroid is modulated as compared to when a corticosteroid alone is administered to the subject. In one embodiment the , agent is an IL-18 antagonist. In another embodiment the agent is an , interleukin-12 (IL-12) antagonist. In yet another embodiment the agent is an , NK cell antagonist. In a preferred embodiment the agent is an inhibitor of a , caspase family …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 12, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 12, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 12, 2020.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.