A method for making infectious, propagation defective tr339 virus particles and helper cells therefor
CA 2281858 C · Owner: Johnston, Robert E. · Inventors: Simpson, Dennis A.; Klimstra, William B.; Johnston, Robert E.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides a method of delivering immunogenic or therapeutic proteins to bone marrow cells using alphavirus vectors. The alphavirus vectors disclosed herein target specifically to bone marrow tissue and viral genomes persist in bone marrow for at least three months postinfection. No or very low levels of virus were detected in quadricep brain, and sera of treated animals. The sequence of a consensus Sindbis cDNA clone pTR339, and infectious RNA transcripts infectious virus particles, and , pharmaceutical formulations derived therefrom are also disclosed. The sequence of the genomic RNA of the Girdwood S.A. virus and cDNA clones, infectious RNA , transcripts infectious …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed February 18, 1998 and granted January 25, 2011. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended February 18, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by February 18, 2020.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.