Assays, agents, therapy and diagnosis relating to modulation of cellular dna repair activity
CA 2277481 A1 · Owner: Cancer Research Campaign Technology Limited · Inventors: Critchlow, Susan Elizabeth; Jackson, Stephen Philip
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A yeast homologue of mammalian DNA ligase IV is provided and a role for DNA ligase IV established in the Ku-associated DNA repair pathway. Additionally interactions between DNA ligase IV and XRCC4 and interaction between XRCC4 , and DNA-PKcs/Ku are established providing for assays for agents which modulate such interactions and therefore cellular DNA repair activity. Such agents are useful in treatment of cancers retroviral infections, immune , system disorders and other conditions in which cellular DNA repair activity plays a role. Individuals with a predisposition to a disorder in which DNA repair plays a role may be diagnosed, by screening for the presence or absence of a defect …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 13, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended January 13, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 13, 2020.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.