Quinoline and quinazoline compounds useful in therapy, particularly in the treatment of benign prostatic hyperplasia

Abstract From the Canadian patent

Compounds of formula (I), wherein R1 represents C1-4 alkoxy optionally substituted by one or more fluorine atoms; R2 represents H or C1-6 alkoxy optionally substituted by one or more fluorine atoms; R3 represents a 5- or 6membered heterocyclic ring, the ring being optionally substituted; R4 represents a 4-, 5-, 6- or 7-membered heterocyclic ring the ring being , optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring the ring system as a whole being optionally substituted; X represents CH or N; and L is absent, or represents a cyclic group of formula (Ia) or represents a , chain of formula (Ib) and pharmaceutically acceptable salts thereof; are useful in therapy, in …