Contryphan peptides
CA 2270284 A1 · Owner: Jimenez, Elsie C. · Inventors: Olivera, Baldomero M.; Cruz, Lourdes J.; Jimenez, Elsie C.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention is directed to contryphan peptides having 6-12 amino acids, preferably including one or more D-tryptophan residues. More specifically, the present invention is directed to contryphan peptides having the general formula Xaa1-Cys-Xaa2-Xaa3-Glu-Pro-Trp-Cys (SEQ ID NO:1) wherein , Xaa1 is Gly or des-Xaa1, Xaa2 is Pro or 4-trans-hydroxyproline and Xaa3 is D- Trp or L-Trp, preferably D-Trp. The present invention is further directed to the peptides contryphan R and des-Gly1 contryphan R. In contryphan R Xaa1 is , Gly and Xaa3 is D-Trp. These contryphans are useful as anticonvulsant or neuroprotective agents.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 7, 1997. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended November 7, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 7, 2019.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.