Use of bisphenolic compounds to treat type ii diabetes

Abstract From the Canadian patent

This invention is directed to methods for treatment of non-insulin-dependent diabetes mellitus, for reducing blood glucose levels or hyperglycemia. The , methods entail administering to a mammal in need of such treatment a therapeutically effective amount of a composition whose active ingredient consists essentially of a compound of structure (I) or a pharmaceutically acceptable salt thereof. In the compound R and R' are independently H or a C1- C20 alkyl or C2-C20 alkenyl group which may be substituted or unsubstituted. Alternatively, R and R' are such that together a cycloalkyl or cycloalkenyl ring is formed. In the chain linking the two phenolic derivatives each of (C(R)=C(R')) or …