Non-invasive administration of adeno-associated viral vectors
CA 2266619 A1 · Owner: Snyder, Richard · Inventors: Mulligan, Richard; Mcarthur, James; Snyder, Richard
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides new methods of administering recombinant AAV vectors for effective, long-term expression of a gene of interest in animals including humans. Provided herein are methods of subcutaneously injecting recombinant AAV vectors containing a gene of interest encoding any diffusible polypeptide, ribozyme, nucleic acid, or antisense oligonucleotide for gene therapy. The methods of this invention provide significant advantages including the ability to deliver any diffusible polypeptide or nucleic acid of a defined size via subcutaneous injection and obtain high-level long-term , expression in regions approximate or distant from the site of subcutaneous injection.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 25, 1997. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended September 25, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 25, 2019.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.