Production of nabumetone or precursors thereof
CA 2265751 A1 · Owner: Albemarle Corporation · Inventors: Theriot, Kevin J.; Becnel, Brian F.; Sabahi, Mahmood
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
In producing nabumetone or precursors thereof use is made of 2-bromo-6-, methoxynaphthalene formed by: (a) methylating 6-bromo-2-naphthol with methyl bromide or methyl chloride, in a halogen-free liquid solvent comprising at least 40 % by weight of one or more compounds of the formula RZ where R is a hydrogen atom or an alkyl group, and Z is a hydroxyl group or a cyanide group with the proviso that if Z is a cyanide group R is an alkyl group, and in the , presence of at least one strong base; and (b) recovering and purifying 2-bromo- 6-methoxynaphthalene so formed. The 6-bromo-2-naphthol in turn is preferably formed by reacting 1,6-dibromo-2-naphthol with hydrogen in a …
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed October 21, 1997. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended October 21, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 21, 2019.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.