Methods using cre-lox for production of recombinant adeno-associated viruses
CA 2264499 A1 · Owner: Phaneuf, Daniel · Inventors: Phaneuf, Daniel; Wilson, James M.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Methods for efficient production of recombinant AAV are described. In one aspect, three vectors are introduced into a host cell. A first vector directs expression of cre recombinase, a second vector contains a promoter a spacer , sequence flanked by loxP sites and rep/cap and a third vector contains a , minigene containing a transgene and regulatory sequences flanked by AAV ITRs. In another aspect, the host cell stably or inducibly expresses cre recombinase and two vectors carrying the other elements of the system are introduced into the host cell.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 4, 1997. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended September 4, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 4, 2019.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.