An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase
CA 2264482 A1 · Owner: The Trustees Of The University Of Pennsylvania · Inventors: Wilson, James M.; Chen, Nancie
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Methods for efficient production of recombinant AAV are described. In one aspect, three vectors are introduced into a host cell. A first vector directs expression of T7 polymerase. A second vector carries rep and cap under the control of the T7 promoter. A third vector contains a rAAV cassette which contains a minigene flanked by AAV ITRs. In a second aspect the host cell is , stably transfected to contain a plasmid bearing one of the required vector components and the host cell is double transfected/infected.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 4, 1997. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended September 4, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 4, 2019.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.