5-substituted and 5,5-disubstituted-3,4-dihydroxy-2(5h)-furanones and methods of use therefor
CA 2264000 A1 · Owner: Ziemniak, John A. · Inventors: Ziemniak, John A.; Johnson, Robert E.; Hopper, Allen T.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to synthetic methods for the production of both optically active and racemic 5,5-disubstituted-3,4-dihydroxy-2(5H)-furanones; 5-(4-aryl)-3-butynyl-3,4-dihydroxy-2(5H)-furanones; 5-(2-arylthio)ethyl-3,4dihydroxy-2(5H)-furanones; and 5-(2-aryloxy)ethyl-3,4-dihydroxy-2(5H)furanones. This invention further relates to the use of the above mentioned compounds as anti-inflammatory agents through their action as mixed inhibitors of lipid peroxidation, 5-lipoxygenase, cyclooxygenase-1 and cyclooxygenase-2. The invention further relates to the use of such compounds in the treatment of chronic inflammatory disorders such as asthma rheumatoid arthritis, inflammatory …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 22, 1997. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended August 22, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 22, 2019.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.