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Peptides promoting the activation of latent tgf-.beta. and method for screening tgf-.beta. activity regulators

CA 2259956 A1 · Owner: Shibata, Kenji · Inventors: Shibata, Kenji; Yamasaki, Motoo; Sato, Yasufumi

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Abstract From the Canadian patent

Peptides represented by the following general formula (I) and having the activity of promoting the liberation of active TGF-.beta. from latent TGF- .beta. or the activity of promoting the binding of latent TGF-.beta. to cell membrane; a method for screening compounds for preventing or treating diseases in which TGF-.beta. participates by assaying the above activities; and the compounds thus obtained. The peptides and compounds described above are useful as remedies or preventives for cancer, diabetic retinitis atherosclerosis, etc. General formula (I): R1-A-R2 wherein R1 represents hydrogen, optionally substituted alkanoyl, etc.; R2 represents hydroxy or optionally substituted alkoxy …

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed May 12, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 12, 2018.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 12, 2020.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledMay 12, 1998
GrantedNo grant recorded
Term endedMay 12, 2018
Patent numberCA 2259956 A1
Classification (IPC)C07K14/49 +2 more

Timeline

Timeline From CIPO dates

1999200120032005200720092011201320152017Application filedMay 12, 1998Term endedMay 12, 2018

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.