Process for the preparation of (s)- or (r)-3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid
CA 2259954 C · Owner: Lonza Ag · Inventors: Naughton, Andrew; Tinschert, Andreas; Shaw, Nicholas
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Described are new micro-organisms and a new enzyme capable of using as sole source of nitrogen the propionic acid amide of formula (VI) in racemate form , or as optically active isomers. Described also is a method of preparing (S) - or (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid of formulas (I) and (II) starting from trifluoroaceto-acetic ester. The first three process steps are chemical, the fourth process step microbiological.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 10, 1997 and granted March 6, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended July 10, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 10, 2019.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.