1,4-di-sustituted piperidines as muscarinic antagonists
CA 2259655 C · Owner: Lowe, Derek B. · Inventors: Green, Michael J.; Asberom, Theodros; Lowe, Derek B.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
1,4-Di-substituted piperidine muscarinic antagonists of formula (I) or a pharmaceutically acceptable salt, ester or solvate thereof, wherein X is a , bond -O-, -S-, -SO-, -SO2-, -CO-, -C(OR7)2- -CH2-O-, -O-CH2-, -CH=CH-, -CH2-, -CH(C1-C6 alkyl)- -C(C1-C6 alkyl)2-, -CONR17-, -NR17CO-, -SO2NR17- or - NR17SO2-; R is C3-C6 cycloalkyl, (a), (b) (c), (d), (e), optionally , substituted phenyl or optionally substituted pyridyl; R1 is H -CN, -CF3, alkyl, cycloalkyl, cycloalkenyl alkenyl, -COR15, -COO(alkyl, aryl, heteroaryl alkylaryl or alkylheteroaryl), alkylaryl alkylheteroaryl or -, CON(R13)2; R2 is cycloalkyl cycloalkenyl, t-butoxycarbonyl or optionally substituted 4-piperidinyl; R3 and R4 are …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 8, 1997 and granted May 13, 2003. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended July 8, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 8, 2019.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.