Pro-protein converting enzyme
CA 2259129 A1 · Owner: Chretien, Michel · Inventors: Reudelhuber, Tim; Leclerc, Guy; Day, Robert
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A cDNA clone encoding the human prohormone convertase PC5 was isolated from human adrenal gland messenger RNA. The deduced protein sequene would encode a 915 amino acid prepro PC5 which shares a very high degree of homology with the previously cloned rat and mouse homologues. PC5 mRNA is detected in multiple human tissues, including the brain, adrenal and thyroid glands heart, placenta, lung and testes. PC5 mRNA was undetectable in the liver and is present at lower levels in skeletal muscle kidney, pancreas, small intestine , and stomach. Co-transfection of human PC5 and human prorenin expression vectors in cultured GH4Cl cells leads to secretion of active renin. The activation of …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 25, 1997. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended July 25, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 25, 2019.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.