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Process for the inactivation of genes which code for enzymes for the catabolism of phenyl acetate, plasmids involved in such process and strains transformed therewith

CA 2258562 A1 · Owner: Rodriguez Saiz, Marta · Inventors: Diez Garcia, Bruno; Fernandez Canon, Jose Manuel; Rodriguez Saiz, Marta

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Abstract From the Canadian patent

Process for inactivating genes which code for enzymes of the phenyl acetate catabolism, plasmids containing them and strains transformed therewith. The process applies preferably to the gene pahcA of A.nidulans and to the gene pahA of P. chrysogenum, genes which code respectively for competitor enzymes for this substrate with the biosynthetic enzymes of penicillin. The non expression of said enzymes favors the synthesis of this antibiotic increasing , its production, with a smaller demand of phenyl acetate per culture unit.

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed April 17, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended April 17, 2018.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 17, 2020.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledApril 17, 1998
GrantedNo grant recorded
Term endedApril 17, 2018
Patent numberCA 2258562 A1
Classification (IPC)C12N15/80 +2 more

Timeline

Timeline From CIPO dates

1999200120032005200720092011201320152017Application filedApril 17, 1998Term endedApril 17, 2018

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.