Enantiomer separation from chromane acid esters
CA 2258032 A1 · Owner: Reubold, Helmut · Inventors: Reubold, Helmut; Devant, Ralf M.; Schulte, Michael
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to processes for the chromatographic separation of enantiomeric esters from 2-alkanoyl-chromane derivatives of the formula (I) in which Z is -(CH2)n1-(CHA)n2-(CH2)n3, where n1 = 0 1, 2 or 3, n2 = 0 or 1, n3 , = 0, 1, 2 or 3 with the proviso that n1 + n2 + n3 < 4 R6, R7, R8 and R9 are , mutually independently H A, OA, phenoxy, OH, F, Cl, Br, I, CN, CF3 NO2, NH2, NHA, NA2, Ac, Ph, cycloalkyl with 3 to 7 atoms -CH2NH2, -CH2NHA, -CH2NA2, -, CH2NHAc or -CH2NHSO2CH3 where two neighbouring radicals may also be an alkylene chain with 3 or 4 C atoms, A is alkyl with 1 to 6 C atoms Ac is , alkanoyl with 1 to 10 C atoms or aroyl with 7 to 11 C atoms Ph is , unsubstituted or …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 7, 1997. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 7, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 7, 2019.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.