Liquisolid systems and methods of preparing same

Abstract From the Canadian patent

Liquisolid systems are acceptably flowing and compressible powdered forms of liquid medications. According to the concept of liquisolid systems liquid , liphophilic drugs or water-insoluble drugs dissolved in suitable non-volatile solvents may be converted into free-flowing and readily compressible powders by simple admixture with selected powder excipients referred to as carrier and coating materials; a schematic outline of steps may be drawn for the process. Various grades of microcrystalline or amorphous cellulose may be used as carriers, whereas very fine particle size silica powders may be used as coating materials. Based on the theory that the carrier and coating materials can …