Indole derivatives useful as endothelin receptor antagonists
CA 2253876 A1 · Owner: James, Kim · Inventors: Rawson, David James; James, Kim; Dack, Kevin Neil
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Compounds of formula (I), and their pharmaceutically acceptable derivatives wherein R1 and R2 are optional substituents and independently represent C1-6 alkyl, C2-6 alkenyl optionally substituted by CO2H or CO2(C1-6 alkyl) C2-6 , alkynyl, halogen, C1-3 perfluoroalkyl (CH2)mAr1, (CH2)mHet1, (CH2)mCONR7R8, (CH2)mCO2R8 O(CH2)qCO2R8, (CH2)mCOR8, (CH2)mOR8, O(CH2)pOR8 (CH2)mNR7R8, CO2(CH2)qNR7R8, (CH2)mCN, S(O)nR8 SO2NR7R8, CONH(CH2)mAr1 or CONH(CH2)mHet1; R3 represents H, C1-6 alkyl, (CH2)pNR9R10 SO2R10, SO2NR9R10, (CH2)mCOR10, C2-, 6 alkenyl C2-6 alkynyl, (CH2)mCONR9R10, (CH2)mCO2R10 (CH2)pCN, (CH2)pR10 or , (CH2)pOR10; R4 represents H or C1-6 alkyl; R5 represents H or OH; R6 represents …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 11, 1997. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended April 11, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 11, 2019.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.