8-hydrocarbyl substituted benzodizocine derivatives, their preparation and their use as protein kinase c (=pkc) modulators
CA 2253463 A1 · Owner: Ma, Dawei · Inventors: Kozikowski, Alan P.; Ma, Dawei; Glazer, Robert I.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Compounds of formula (I) wherein R1 is H (C1-C5)alkyl, ORa, SRa, N(Ra)(Rb), halo NO2, NHC(O)(C1-C4)alkyl or NHOH; R2 is a (C5-C22) hydrocarbyl group optionally comprising 1-3 double bonds 1-2 triple bonds or a mixture thereof, or (C6-C12)aryl(C2-C10)alkyl wherein the alkyl moiety optionally comprises 1- 2 double bonds, 1-2 triple bonds or a mixture thereof; wherein said (C5-C22) hydrocarbyl group or said (C6-C12)aryl(C2-C10)alkyl may optionally be substituted with 1 or 2 substituents independently selected from the group consisting of halo, hydroxy, cyano, nitro (C1-C5)alkyl, (C1-C5)alkoxy, trifluoromethyl trifluoromethoxy, -C(=O)O(C1-C5)alkyl, and N(Re)(Rf); R1 and R2 together are …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 9, 1997. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 9, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 9, 2019.
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Timeline
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.