Hybrid proteins which form heterodimers
CA 2245877 C · Owner: Laboratoires Serono S.A. · Inventors: Jameson, Bradford A.; Campbell, Robert K.; Chappel, Scott C.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A hybrid protein includes two coexpressed amino acid sequences forming a dimer. Each sequence contains the binding portion of a receptor such as TBP1 , or TBP2, or a ligand, such as IL-6 IFN-.beta. and TPO, linked to a subunit of a heterodimeric proteinaceous hormone, such as hCG. Each coexpressed sequence contains a corresponding hormone subunit so as to form a heterodimer upon expression. Corresponding DNA molecules expression vectors and host cells are also disclosed as are pharmaceutical compositions and a method of producing such proteins.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed February 20, 1997 and granted September 3, 2013. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended February 20, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by February 20, 2019.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.